Meet TYPOlight, a powerful Web content management system that specializes in accessibility (back end and front end) and uses XHTML and CSS to generate W3C/WAI compliant pages.
Accessibility

A growing number of countries around the world have introduced legislation which either directly addresses the need for websites to be accessible to people with disabilities, or which addresses the more general requirement for people with disabilities not to be discriminated against. TYPOlight does not treat accessibility as just an additional feature and is thoroughly accessible.

http://blog.fedecarg.com/2009/05/13/is-this-the-best-open-source-cms-ever-created/

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